LARITUM SB

LARITUM-SB
Ceftriaxone 1000 mg & Sulbactam 500 mg Injection

Tagline:
Powerful Dual Action Against Resistant Bacterial Infections

Indication:
Laritum-SB is indicated for the treatment of various bacterial infections, particularly those caused by resistant strains of bacteria, such as Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa). It can be used in the following infections:

• Respiratory Tract Infections: Pneumonia, bronchitis, and other lower respiratory tract infections.
• Urinary Tract Infections: Complicated and uncomplicated UTIs caused by resistant bacteria.
• Intra-abdominal Infections: Including peritonitis and intra-abdominal abscesses.
• Skin and Soft Tissue Infections: Cellulitis, wound infections, and abscesses.
• Bone and Joint Infections: Osteomyelitis, septic arthritis.
• Septicemia: Bloodstream infections caused by susceptible organisms.

Mode of Action:
Laritum-SB combines the broad-spectrum activity of Ceftriaxone, a third-generation cephalosporin antibiotic, with Sulbactam, a beta-lactamase inhibitor. Ceftriaxone works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Sulbactam enhances this effect by inhibiting beta-lactamase enzymes produced by resistant bacteria, thereby restoring the efficacy of ceftriaxone against beta-lactamase-producing organisms. This combination makes Laritum-SB highly effective against resistant bacterial strains, offering a robust alternative to ceftriaxone-tazobactam, especially in infections caused by E. coli and P. aeruginosa.

How to Take Laritum-SB:

• Administration: Laritum-SB is administered as an intravenous (IV) or intramuscular (IM) injection. The preparation and administration should be performed by a healthcare professional.
• Reconstitution: For IV or IM use, Laritum-SB should be reconstituted with the appropriate diluent, according to the manufacturer’s instructions or healthcare provider’s guidance.
• Timing: The dosing schedule is typically determined by the severity and type of infection. It is usually given once or twice daily, as advised by the healthcare provider.

Dosage:

• Adults: The typical adult dose is 1000 mg of ceftriaxone combined with 500 mg of sulbactam, administered once or twice daily, depending on the infection severity.
• Pediatrics: Dosing in children should be based on body weight, typically calculated by the healthcare provider.

Possible Side Effects:
While Laritum-SB is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Injection Site Reactions: Pain, swelling, or redness at the injection site.
• Gastrointestinal Issues: Diarrhea, nausea, vomiting, or abdominal discomfort.
• Allergic Reactions: Rash, itching, or hives. Severe allergic reactions (anaphylaxis) are rare but require immediate medical attention.
• Hematologic Changes: Rarely, ceftriaxone may cause changes in blood counts, such as leukopenia, thrombocytopenia, or anemia. Regular monitoring may be required during prolonged therapy.
• Liver Enzyme Elevations: Transient increases in liver enzymes (AST, ALT) may occur. Liver function should be monitored, particularly in patients with pre-existing liver conditions.
• Superinfection: Prolonged use of antibiotics can sometimes lead to the overgrowth of non-susceptible organisms, such as fungi.

Precautions:

• Renal and Hepatic Function: Use with caution in patients with renal or hepatic impairment. Dose adjustments may be necessary.
• Allergic Reactions: Patients with a history of allergies to cephalosporins or other beta-lactam antibiotics should use Laritum-SB with caution.
• Drug Interactions: Inform your healthcare provider of all medications you are taking, as Laritum-SB can interact with certain drugs, including calcium-containing solutions.
• Superinfection Risk: Monitor for signs of secondary infections due to prolonged antibiotic use.

Consult Your Doctor:

• Before starting Laritum-SB if you have any known allergies, particularly to beta-lactam antibiotics, or if you have liver or kidney disease.
• If you experience any severe or unusual symptoms, particularly signs of an allergic reaction or gastrointestinal distress.
• For guidance on the proper use of Laritum-SB and to discuss any concerns regarding your treatment plan.

Clear RESISTANT INFECTIONS with Confidence

Disclaimer: This information is for general knowledge only and should not be considered medical advice. Always consult with a healthcare professional for personalized guidance.