CEFLAN 1.5g

Composition:

• Voglibose 0.2 mg
• Glimepiride 2 mg
• Metformin 500 mg

Description:
Voglivin MG2 is a combination tablet designed for the management of type 2 diabetes mellitus. This formulation combines three effective antidiabetic agents—Voglibose, Glimepiride, and Metformin—to provide comprehensive glycemic control by addressing multiple aspects of blood glucose regulation.

Indications:
Voglivin MG2 is indicated for:

• Management of type 2 diabetes mellitus in adults.
• Improvement of glycemic control in patients inadequately controlled with Metformin, Glimepiride, or Voglibose alone.
• As an adjunct to diet and exercise to enhance blood glucose control.

Mechanism of Action:

• Voglibose: An alpha-glucosidase inhibitor that slows the absorption of carbohydrates in the intestines, reducing postprandial blood glucose levels.
• Glimepiride: A sulfonylurea that stimulates insulin release from pancreatic beta cells, helping to lower blood glucose levels.
• Metformin: Reduces hepatic glucose production and enhances insulin sensitivity in peripheral tissues, leading to improved glucose uptake and utilization.

Dosage and Administration:

• The usual dose is one tablet of Voglivin MG2 daily, taken with the morning meal to minimize gastrointestinal side effects.
• Dosage adjustments should be made based on individual patient response and blood glucose levels.

Contraindications:

• Hypersensitivity to Voglibose, Glimepiride, Metformin, or any component of the tablet.
• Severe renal impairment or significant liver dysfunction.
• Type 1 diabetes mellitus or diabetic ketoacidosis.
• Pregnancy and breastfeeding.

Warnings and Precautions:

• Monitor renal function regularly due to the Metformin component.
• Caution is advised in patients with a history of gastrointestinal issues, hypoglycemia, or those taking other antidiabetic medications.
• Discontinue use and consult a healthcare provider if symptoms of lactic acidosis (e.g., unusual muscle pain, difficulty breathing) or severe hypoglycemia occur.

Side Effects:
Common side effects may include:

• Nausea
• Diarrhea
• Abdominal pain
• Headache

Serious side effects, although rare, may include:

• Lactic acidosis
• Severe hypoglycemia
• Liver dysfunction

Drug Interactions:

• May interact with other antidiabetic medications, corticosteroids, and diuretics.
• Caution is advised with drugs affecting glucose metabolism or renal function.

Storage:

• Store in a cool, dry place, away from direct sunlight.
• Keep out of reach of children.

Packaging:

• Available in blister packs of 10 tablets.

Disclaimer:
This information is provided for educational purposes only. For personalized medical advice and treatment options, consult a healthcare professional.