Cefuroxime is a cephalosporin antibiotic used to treat bacterial infections. Here are some important safety precautions to follow when using cefuroxime injections:

Allergies

Inform your doctor if you have any known allergies to cefuroxime, other cephalosporins, or penicillins.

Cross-allergies: There’s a risk of cross-allergies between these antibiotic classes.

Medical History

Tell your doctor about any other medical conditions you have, especially:

• Kidney disease
• Liver disease
• Seizure disorders
• Intestinal diseases (like colitis)
• Pregnancy and Breastfeeding

Consult your doctor if you’re pregnant or breastfeeding. Cefuroxime may pass into breast milk.

Other Medications

Inform your doctor about all other medications you’re taking, including prescription drugs, over-the-counter medications, and herbal supplements. Cefuroxime may interact with certain medications.

Side Effects

Watch for side effects: Common side effects include diarrhea, nausea, vomiting, and injection site reactions.

Serious side effects: Contact your doctor immediately if you experience:

Severe allergic reactions (e.g., difficulty breathing, swelling of the face or throat)

Seizures

• Unusual bleeding or bruising
• Severe diarrhea (may be a sign of a serious infection)
• Proper Administration
• Follow your doctor’s instructions for proper administration of the injection.
• Don’t self-inject unless instructed by your healthcare provider.

Ceflan Injection
Powerful Antibiotic for Effective Infection Control

Composition: Each vial contains:

• Cefuroxime Sodium 1.5 gm

Indications: Ceflan is indicated for the treatment of a wide range of bacterial infections, including:

• Respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Bone and joint infections
• Gynecological infections
• Intra-abdominal infections

Mechanism of Action: Ceflan contains Cefuroxime, a second-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis. This leads to the destruction of susceptible bacteria, making it effective against a broad spectrum of Gram-positive and Gram-negative pathogens.

Dosage and Administration: The dosage of Ceflan should be determined by the healthcare provider based on the type and severity of the infection. It is usually administered intravenously:

• Adults: 1.5 gm every 8 to 12 hours, depending on the infection severity.
• Children: Dosage to be determined by the physician.

Administration Instructions:

• Ceflan should be reconstituted and diluted according to the manufacturer’s instructions.
• The solution should be administered slowly by intravenous infusion over a period of 30 to 60 minutes.

Warnings and Precautions:

• Allergy Alert: Use with caution in patients with a known allergy to cephalosporins or penicillins.
• Renal Impairment: Dose adjustment may be required in patients with renal impairment.
• Superinfection: Prolonged use may result in superinfection with resistant organisms.

Side Effects: Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Rash
• Pain at the injection site

Serious side effects are rare but may include:

• Allergic reactions (e.g., anaphylaxis)
• Severe gastrointestinal symptoms (e.g., pseudomembranous colitis)
• Hepatic or renal function disturbances

Contraindications:

• Hypersensitivity to Cefuroxime or other cephalosporins.
• Severe renal impairment without appropriate dose adjustment.

Storage:

• Store at 25°C (77°F).
• Protect from light and moisture.
• Reconstituted solutions should be used immediately.

Packaging:

• Available in vials containing 1.5 gm of Cefuroxime Sodium per vial.

Remember: This information is a general overview and doesn’t replace specific medical advice. Always consult with your doctor or pharmacist for personalized guidance.

In Surgical Prophylaxis

Ceflan

Cefuroxime Sodium 1.5 gm Injection

• Superior coverage: Gram-positive Gram-negative, including

β-lactamase-producing strains.

• Proven Safety Profile: Low potential for cross-reactivity in patients allergic to penicillin.

• Enhanced Tissue Penetration: Achieves high tissue concentrations.

• Sustained antibacterial action: Resistant to degradation by most β-lactamases

DOSAGE CARD	DOSING	FREQUENCY
ADULTS	Standard Dose: 1.5 g administered intravenously (IV) as a single dose.	To be administered within 30 to 60 minutes prior to the surgical incision
PEDIATRIC PATIENTS	30 to 50 mg/kg IV, administered as a single dose
FOR PROLONGED SURGERIES	If the surgery lasts longer than 3-4 hours, or if there is significant blood loss, an additional 750 mg to 1.5 g dose may be given during the procedure.
POST-SURGERY	No further doses are needed after the surgical procedure for standard prophylaxis, but if there is a high risk of infection, or in the case of contaminated surgeries, additional doses may be administered at 8-hour intervals TILL 48 hours postoperatively.

* FDA Drug labeling for Cefuroxime^Skin and soft tissue infection 

Ceflan: Your trusted Shield for Surgical Prophylaxis 

Disclaimer: This information is for general knowledge only and should not be considered medical advice. Always consult with a healthcare professional for personalized guidance.