Active Ingredients:
- Teneligliptin Hydrobromide Hydrate 20 mg
Description:
Tenelar-20 is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Teneligliptin helps to regulate blood glucose levels by enhancing the body’s natural ability to control glucose levels through the incretin system.
Indications:
Tenelar-20 is indicated for:
- Management of type 2 diabetes mellitus in adults.
- Use as an adjunct to diet and exercise to improve glycemic control.
Mechanism of Action:
Teneligliptin inhibits the DPP-4 enzyme, which leads to increased levels of incretin hormones (such as GLP-1 and GIP). These hormones stimulate insulin secretion and reduce glucagon levels, resulting in improved blood glucose control.
Dosage and Administration:
- The recommended dose is one tablet of Tenelar-20 daily, taken with or without food.
- Dosage adjustments are not typically required for renal impairment but should be done based on individual patient needs and response to treatment.
Contraindications:
- Hypersensitivity to Teneligliptin or any component of the tablet.
- Type 1 diabetes mellitus.
- Diabetic ketoacidosis.
Warnings and Precautions:
- Monitor for signs of pancreatitis; discontinue use if symptoms such as severe abdominal pain occur.
- Use with caution in patients with a history of renal impairment.
- May require dose adjustments or close monitoring when used in combination with other antidiabetic medications.
Side Effects:
Common side effects may include:
- Headache
- Nasopharyngitis
- Diarrhea
- Upper respiratory tract infection
Serious side effects, although rare, may include:
- Pancreatitis
- Severe allergic reactions
- Renal impairment
Drug Interactions:
- May interact with other antidiabetic agents, particularly those that affect glucose metabolism.
- Caution is advised when used with medications that have renal excretion.
Storage:
- Store in a cool, dry place, away from direct sunlight.
- Keep out of reach of children.
Packaging:
- Available in blister packs of 10 tablets.
Disclaimer:
This information is provided for educational purposes only. For personalized medical advice and treatment options, consult a healthcare professional.
