Active Ingredients:
- Teneligliptin 20 mg
- Metformin SR 500 mg
Description:
Tenelar-M combines Teneligliptin and Metformin in a single tablet, providing a dual mechanism for managing type 2 diabetes mellitus. This formulation offers the benefits of a DPP-4 inhibitor and prolonged-release Metformin to help achieve optimal blood glucose control.
Indications:
Tenelar-M is indicated for:
- Management of type 2 diabetes mellitus in adults.
- As an adjunct to diet and exercise to improve glycemic control.
- Use in patients inadequately controlled with Metformin or Teneligliptin alone.
Mechanism of Action:
- Teneligliptin: A DPP-4 inhibitor that increases incretin hormone levels, which enhances insulin secretion and lowers glucagon levels, thereby improving glucose control.
- Metformin SR: A prolonged-release formulation that decreases hepatic glucose production and increases insulin sensitivity in peripheral tissues, facilitating better glucose uptake and utilization.
Dosage and Administration:
- The recommended dose is one tablet of Tenelar-M daily, taken with or after the morning meal.
- Dosage adjustments may be needed based on individual patient response and blood glucose levels.
Contraindications:
- Hypersensitivity to Teneligliptin, Metformin, or any component of the tablet.
- Severe renal impairment or significant liver dysfunction.
- Type 1 diabetes mellitus or diabetic ketoacidosis.
- Pregnancy and breastfeeding.
Warnings and Precautions:
- Monitor renal function regularly due to the Metformin component.
- Caution is advised in patients with a history of gastrointestinal issues or hypoglycemia.
- Discontinue use and seek medical attention if symptoms of lactic acidosis (e.g., unusual muscle pain, difficulty breathing) or severe hypoglycemia occur.
Side Effects:
Common side effects may include:
- Nausea
- Diarrhea
- Headache
- Abdominal pain
Serious side effects, although rare, may include:
- Lactic acidosis
- Severe hypoglycemia
- Pancreatitis
Drug Interactions:
- May interact with other antidiabetic medications, particularly those affecting glucose metabolism.
- Caution is advised with medications that have renal excretion or those affecting renal function.
Storage:
- Store in a cool, dry place, away from direct sunlight.
- Keep out of reach of children.
Packaging:
- Available in blister packs of 10 tablets.
Disclaimer:
This information is provided for educational purposes only. For personalized medical advice and treatment options, consult a healthcare professional.
